The Iowa State Insect Collection (ISIC), which is housed in the Department of Entomology, Iowa State University, is the only major entomological collection in the state of Iowa.
The collection maintains global holdings for taxa of prior and current research focus (e.g., Miridae, Siphonaptera, Blephariceridae, and Mycetophilidae). ISIC is of national and international importance because it is a primary source of insect specimens from prairie habitats of Iowa, and because of significant collections by H.H. Knight, J.A. Slater, and H.M Harris (Hemiptera), J.L. Laffoon and W.A. Rowley (Diptera), R.L. Lewis (Siphonaptera), and G W. Courtney (Diptera and aquatic insects).
Although the majority of specimens are from Iowa and the upper Midwest, the collection houses abundant representation from other North American localities. Significant international collections include specimens from Asia (especially India, Nepal, and Thailand), Central America (especially Costa Rica), South America (especially Patagonia), and Australasia.