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Pesticide Toxicology Laboratory

ISU Entomology / Pesticide Toxicology Laboratory / Mode of action of Bacillus thuringiensis toxin CryIIIA: An analysis of toxicity in Leptinotarsa decemlineata (Say) and Diabrotica undecimpunctata howardi Barber

Mode of action of Bacillus thuringiensis toxin CryIIIA: An analysis of toxicity in Leptinotarsa decemlineata (Say) and Diabrotica undecimpunctata howardi Barber

Authors: Slaney, A.C., Robbins, H.L., English, L.
Journal, Volume, Year: Insect Biochemistry and Molecular Biology, volume 22(1):9-18, 1992
Summary

This paper discusses the mode of action of Bt toxin CryIIIA and the differences in sensitivity between Leptinotarsa decemlineata and Diabrotica undecimpunctata howardi. L. decemlineata was 2000 fold more sensitive to Bt toxin CryIIIA than D. undecimpunctata howardi. The authors suggest that the failure of CryIIIA in D. undecimpunctata howardi is due, in part, to the poor ability of CryIIIA to bind to membrane receptors and enhance membrane permeability.

Comments

This article is useful for its study of the mode of action of Bt toxins