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Osborn Research Club

ISU Entomology / Osborn Research Club / Deep Brain Stimulation using Magnetic Fields in Transcranial Magnetic Stimulation

Deep Brain Stimulation using Magnetic Fields in Transcranial Magnetic Stimulation

Molecular Biology Building
November 14, 2011
David Jiles, Distinguished Professor and Chair, Electrical and Computer Engineering, ISU
New applications for transcranial magnetic stimulation (TMS) are developing rapidly for both diagnostic and therapeutic purposes. Such brain disorders as Parkinson’s disease and vascular dementia, or the results of traumatic brain injury, concussion, ischaemic stroke are all being looked at with a view to possible treatment using this method. Therefore so also is the demand for improved performance increasing rapidly, particularly in terms of their ability to stimulate deeper regions of the brain and to do so selectively. The coil designs that are used presently are limited in their ability to stimulate the brain at depth and with high spatial focality. Consequently, any improvement in coil performance would have a signifcant impact in extending the usefulness of TMS in both clinical applications and academic research studies. New and improved coil designs have then been developed, modeled and tested as a result of this work. A large magnetizing coil, 300mm in diameter and compatible with a commercial TMS system has been constructed to determine its feasibility for use as a deep brain stimulator. The results of this work have suggested directions that could be pursued in order to further improve the coil designs.